The coordinators of the project:
Ph.D. Yurchuk T.
ORCID https://orcid.org/0000-0002-4993-9129,
Scopus https://www.scopus.com/authid/detail.uri?authorId=56422159300.
DSc Prof. Petrushko M.P.
ORCID: https://orcid.org/0000-0002-9608-0919,
Scopus: https://www.scopus.com/authid/detail.uri?authorId=6508135275,
Relevance of the problem: The war in Ukraine and the difficult environmental situation have caused an increase in oncological diseases. It is important to preserve the fertility of patients before starting gonadotoxic therapy. In addition, constant bombings from the neighboring country have caused an increase in the number of injuries among the population and military personnel, rescuers, etc., which lead to impaired reproductive function. Our department is engaged in the improvement of existing protocols for cryopreservation of mature oocytes, spermatozoa, as well as human embryos in the pre-implantation stages of development. According to the guidelines of the European Society of Human Reproduction and Embryology, in vitro maturation of oocytes is an innovative technology that needs further improvement. The researchers of our department are studying this problem, and are also developing methods of preserving fertility by cryopreservation of immature oocytes. Obtaining new knowledge in this area will give a new impetus to the preservation of human fertility, since the maturation of oocytes in vitro and their cryopreservation has a number of advantages: it is possible to apply to patients of prepubertal and reproductive age; ovarian superovulation is not required or significantly lower doses of gonadotropins are used; there are fewer ethical restrictions when using immature human oocytes compared to embryos.
The goal of the project is to develop a method of cryopreservation and maturation of immature human oocytes in order to preserve fertility in cancer patients.
If you wish to support this direction, please indicate in your payment:
Charitable donation for Support of individual research projects (Yurchuk).
